An explosive new film from Coralie Fargeat, starring Demi Moore, Margaret Qualley and Dennis Quaid.
Winner of Best Screenplay at 2024 Cannes Film Festival.
Demi Moore gives a career-best performance as Elisabeth Sparkle, a former A-lister past her prime and suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid).
She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twentysomething Sue (Margaret Qualley).
The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?
Deliriously entertaining and ruthlessly satirical, Coralie Fargeat’s Cannes sensation turns toxic beauty culture inside out with a be-careful-what-you-wish-for fable for the ages. Explosive, provocative and twisted, THE SUBSTANCE marks the arrival of a thrillingly visionary filmmaker.
One single injection unlocks your DNA.
Starting a new cellular division that will release a better version of yourself.
You just have to share.
One week for one. And one week for the other.
A perfect balance of seven days each.
The only thing not to forget: you can’t escape from yourself.
HOW TO USE
Activate only once.
Stabilize every day.
Switch every seven days. Without exception.
Remember you are one.